General description
Anti-hepatocyte specific antigen, also known as anti-Hep-Par1, recognizes both benign and malignant liver-derived tissues including such tumors as hepatoblastoma, hepatocellular carcinoma, and hepatic adenoma. It recognizes both normal adult and fetal liver tissue. The typical pattern is a granular cytoplasmic staining. This antibody is useful in differentiating hepatocellular carcinomas with adenoid features from adenocarcinomas, either primary in the liver or metastatic lesions to the liver.1-3 In labeling hepatoblastoma, it is useful in differentiating this entity from other small round cell tumors.4,5
Legal Information
Cell Marque is a trademark of Sigma-Aldrich Co. LLC
Linkage
Hepatocyte Specific Antigen (Hep-Par1)(OCH1E5) Positive Control Slides, Product No. 264S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Other Notes
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Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide.
Preparation Note
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Quality
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