Analysis Note

Color (visual): white to light yellow to beigeAppearance of substance (visual): beadsLoading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 0.80 mmol/gSwelling Volume (in DMF): lot specific resultSwelling Volume (in CH₂Cl₂): lot specific resultTotal swelling volume acc. Houben Weyl (in CH₂Cl₂): ≥ 5.2 ml/gTotal swelling volume acc. Houben Weyl (in DMF): ≥ 5.2 ml/gThe polymer matrix is copoly (styrene - 1% DVB) 100 -200 mesh

General description

A hyper acid-labile linker for the Fmoc SPPS of protected peptide amides via mild 1% TFA cleavage [1, 2]. The resin can be readily reductively alkylated to provide a support suited to the synthesis of secondary carboxamides [3].

This resin has also been employed to produce protected peptide fragments in which the C-terminal carboxylic acid group is blocked as a hydroxymethylphenoxy-β-alaninamide ester [4].

The product number for this product was previously 01-64-0059.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 01-64-0059

Packaging

25 g in Plastic bottle