Chlortetracycline hydrochloride, >=75% (HPLC)

Code: C4881-5G D2-231

Application

Chlortetracycline was used in fluorescence assays to detect the Ca+2 influx required for the completion of acrosome reaction in human spermatozoa.

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£43.80 5G
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Application

Chlortetracycline was used in fluorescence assays to detect the Ca+2 influx required for the completion of acrosome reaction in human spermatozoa.

Biochem/physiol Actions

Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens. It inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. It is effective against Gram-positive and to a lesser degree Gram-negative bacteria than tetracycline.Mode of Resistance: Loss of cell wall permeability.

General description

Chemical structure: tetracycline

Other Notes

If stored frozen, chlortetracycline hydrochloride is expected to remain stable at least four years.

Packaging

5, 25, 100 g in glass bottle

antibiotic activity spectrumGram-positive bacteria, Gram-negative bacteria
assay≥91.0% dry basis (HPLC)
formpowder
InChI keyCBHYYLPALVVVEY-LYNLVHCPSA-N
InChI1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1
mode of actionprotein synthesis | interferes
mp210-215 °C (dec.) (lit.)
pKa (25 °C)3.3, 9.3, 7.4
Quality Level200
SMILES stringCl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O
solubility1 M NaOH: 50 mg/mL
storage temp.−20°C
Code
Description
Unit Size
List Price
Qty
C4881-100G
Unit:100G
List Price: £370.00
Source:List Price
ADD
C4881-25G
Unit:25G
List Price: £142.00
Source:List Price
ADD
Cas Number64-72-2
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