Application

NADase from porcine brain has been used in a study to investigate histidine and related compounds resulting from catalyzed ADP-riboslyation. It has also been used in a study to investigate the preparation of arylazide-substituted pyridine adenine dinucleotides for photoaffinity labeling.

Biochem/physiol Actions

Nicotinamide has been shown to inhibit NADase activity.

General description

NADase is a glycohydrolase that catalyzes ADP-ribose transfer.

Packaging

5 g in poly bottle

Physical form

Acetone-dried powder

Unit Definition

One unit will hydrolyze 1.0 µmole of β-NAD to nicotinamide and ADP-ribose per min at pH 7.3 at 37 °C.