General description

Native, human Hsp90. An ~90 kDa heat shock protein constitutively expressed and residues in the cytoplasm. It exists as a dimer and binds to other cellular proteins such as p60^v-src, steroid receptors, heme-regulated protein kinase, actin, and tubulin. Binds to histones with high affinity and induces chromatin condensation.

Native, human Hsp90. A ~90 kDa heat shock protein that is constitutively expressed and resides in the cytoplasm. It exists as a dimer and binds to other cellular proteins such as p60^v-src, steroid receptors, heme-regulated protein kinase, actin, and tubulin. Binds to histones with high affinity and induces chromatin condensation.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Kim, H.R., et al. 1999. J. Biochem. 126, 1025.Schnaider, T., et al. 1999. Life Sci. 65, 2417.Welch, W.J., et al. 1982. J. Biol. Chem. 257, 14949.

Packaging

50 µg in Plastic ampoule

Physical form

In 100 mM NaCl, 50 mM Tris-HCl, 1 mM DTT, pH 7.5.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Warning

Toxicity: Standard Handling (A)