Application

Cell Inhibition Assays (see application reference)r>ELISA (see application reference)r>Flow Cytometry (2.5 µg/ml, see application reference)r>Immunoprecipitation (2.5 µg/ml, see application reference)

General description

Recognizes the α_v integrin chain and all α_v-containing integrins.

Purified mouse monoclonal antibody. Recognizes the α_v integrin chain and all α_v-containing integrins.

This Anti-Integrin α_v (Ab-1) Mouse mAb (272-17E6) is validated for use in Cell Inhibition Assays, ELISA, FC, IP for the detection of Integrin α_v (Ab-1).

Immunogen

human placental α_vβ₃ integrin

Human

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Akiyama, S.K. 1996. Hum. Cell9, 181.Hynes, R.O. 1992. Cell69, 11.Albelda, S.M. and Buck, C.A. 1990. FASEB J.4, 2868.Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol.3, 179.Hynes, R.O. 1987. Cell45, 549.

Cross-reacts with all α_v integrins. Blocks cell adhesion mediated by all α_v integrins and in vivo melanoma growth and angiogenesis (see application references). Variables associated with assay conditions will dictate the proper working dilution.

Packaging

100 µg in Plastic ampoule

Please refer to vial label for lot-specific concentration.

Physical form

In PBS, pH 7.6.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Warning

Toxicity: Standard Handling (A)