Biochem/physiol Actions

Functional ELISA: binds rhC1q (5 µg/ml) in the linear range of 0.25-15 µg/ml.

General description

Recombinant, mouse pentraxin 3, consisting of amino acids 18-381 and expressed in NS0-derived murine myeloma cells with a C-terminal His Tag™. Pentraxin 3, a secreted glycoprotein, exhibits a C-terminal Pentraxin domain and a unique N-terminal domain. Its increased expression may enhance the immune response to protect a host from infection.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Dias, A.A.M. et al. 2001. J. Leukocyte Biol.69, 928.Luchetti, M.M. et al. 2000. Clin. Exp. Immunol.119, 196.Rovere, P. et al. 2000. Blood96, 4300.Bottazzi, B. et al. 1997. JBC. 272, 32817.Goodman A.R. et al. 1996. Cytokine & Growth Factor Rev.7, 191.Introna, M. et al. 1996. Blood87, 1862.Altmeyer, A. et al. 1995. J. Biol. Chem.270, 25584.Lee, G.W. et al. 1993. J. Immunol.150, 1804.Breviario, F. et al. 1992. JBC.267, 22190.Lee, T.H. et al. 1990. Mol. Cell. Biol.10, 1982.Osmand, A.P. et al. 1977. PNAS, USA74, 739.

Packaging

25 µg in Glass bottle

Physical form

Lyophilized from 0.2 µm filtered MOPS, NaCl, CaCl₂, BSA.

Reconstitution

Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.

Reconstitute to 100 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.

Warning

Toxicity: Standard Handling (A)