Monoclonal Anti-CDC14A antibody produced in mouse, clone 1F11, purified immunoglobulin, buffered aqueous solution

Code: sab1404598-100ug D2-231

General description

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae...


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£432.00 100UG
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General description

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. (provided by RefSeq)

Immunogen

CDC14A (NP_003663, 431 a.a. ~ 530 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequencePFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSRLASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPE

Physical form

Solution in phosphate buffered saline, pH 7.4

antibody formpurified immunoglobulin
antibody product typeprimary antibodies
biological sourcemouse
clone1F11, monoclonal
conjugateunconjugated
formbuffered aqueous solution
Gene Informationhuman ... CDC14A(8556)
isotypeIgG2aκ
mol wtantigen ~37.11 kDa
NCBI accession no.NM_003672
Quality Level100
shipped indry ice
species reactivityhuman
storage temp.−20°C
technique(s)indirect ELISA: suitable, western blot: 1-5 µg/mL, indirect immunofluorescence: suitable
UniProt accession no.Q9UNH5
This product has met the following criteria: