Anti-TAF11 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution

Code: sab1411325-100ug D2-231

General description

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is tr...


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General description

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. (provided by RefSeq)

Immunogen

TAF11 (NP_005634.1, 1 a.a. ~ 211 a.a) full-length human protein.SequenceMDDAHESPSDKGGETGESDETAAVPGDPGATDTDGIPEETDGDADVDLKEAAAEEGELESQDVSDLTTVEREDSSLLNPAAKKLKIDTKEKKEKKQKVDEDEIQKMQILVSSFSEEQLNRYEMYRRSAFPKAAIKRLIQSITGTSVSQNVVIAMSGISKVFVGEVVEEALDVCEKWGEMPPLQPKHMREAVRRLKSKGQIPNSKHKKIIFF

Physical form

Solution in phosphate buffered saline, pH 7.4

antibody formpurified immunoglobulin
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
conjugateunconjugated
formbuffered aqueous solution
Gene Informationhuman ... TAF11(6882)
mol wtantigen 23.3 kDa
NCBI accession no.NM_005643.2
Quality Level100
shipped indry ice
species reactivityhuman
storage temp.−20°C
technique(s)western blot: 1 µg/mL
UniProt accession no.Q15544
This product has met the following criteria: