Asenapine maleate, >=98% (HPLC)

Code: a7861-10mg D2-231

Application

Asenapine maleate is a serotonin 5-HT and dopamine D2 receptor antagonist. Asenapine maleate can be used to treat schizophrenia and bipolar mania.

Asenapine...


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£83.90 10MG
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Application

Asenapine maleate is a serotonin 5-HT and dopamine D2 receptor antagonist. Asenapine maleate can be used to treat schizophrenia and bipolar mania.

Asenapine maleate has been used as a stressor in studying the Fos expression in forebrain structures of rat models.

Biochem/physiol Actions

Asenapine maleate is a 5-HT receptor antagonist (5-HT1A,1B, 5-HT2A, 2B, 2C, 5-HT5A, 5-HT6 and 5-HT7), a D2 antagonist, and an antipsychotic.

Features and Benefits

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

General description

Asenapine maleate acts as an antimanic. It belongs to the family of dibenzoxepinopyrrolidines. Asenapine is considered to be a weak inhibitor of cytochrome P450 2D6 (CYP2D6). It increases the level of dopamine, norepinephrine and acetylcholine in brain.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to off-white
formpowder
InChI keyGMDCDXMAFMEDAG-CHHFXETESA-N
InChI1S/C17H16ClNO.C4H4O4/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19;5-3(6)1-2-4(7)8/h2-8,14-15H,9-10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,15-;/m1./s1
originatorMerck & Co., Inc., Kenilworth, NJ, U.S.
Quality Level100
SMILES stringOC(=O)C=C/C(O)=O.CN1C[C@H]2[C@H](C1)c3cc(Cl)ccc3Oc4ccccc24
solubilityH2O: ≥10 mg/mL
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
A7861-50MG
Asenapine maleate, >=98% (HPLC)

Unit:50MG
List Price: £271.00
Source:List Price
ADD
Cas Number85650-56-2
Hazard Class6.1
Un Number2811
Pack Group3
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