Hexamethonium bromide,

Code: h0879-5g D2-231

Application

Hexamethonium bromide has been used:as an autonomic ganglia-blocking agent to study its effects on whisker movement in ratsas a nicotinic receptor antagonist to s...


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Application

Hexamethonium bromide has been used:as an autonomic ganglia-blocking agent to study its effects on whisker movement in ratsas a nicotinic receptor antagonist to study its effects on antigen-induced arthritis (AIA) progression in miceas a non-selective ganglionic nicotinic acetylcholine receptor (nAChR) antagonist to study its effects on cytisine-induced autonomic cardiovascular responses in mice

Biochem/physiol Actions

Hexamethonium bromide is a nicotinic acetylcholine receptor (nAChR) antagonist. It preferentially blocks nicotinic receptors at autonomic ganglia. It can cross the blood-brain barrier only at high doses.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Gene Informationhuman ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143)
InChI keyFAPSXSAPXXJTOU-UHFFFAOYSA-L
InChI1S/C12H30N2.2BrH/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
mp282-285 °C (dec.)
Quality Level200
SMILES string[Br-].[Br-].C[N+](C)(C)CCCCCC[N+](C)(C)C
Code
Description
Unit Size
List Price
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H0879-100G
Hexamethonium bromide,

Unit:100G
List Price: £172.00
Source:List Price
ADD
H0879-25G
Hexamethonium bromide,

Unit:25G
List Price: £52.40
Source:List Price
ADD
Cas Number55-97-0
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