PP242 hydrate, >=98% (HPLC), powder

Code: p0037-5mg D2-231

Application

PP242 hydrate has been used:as a mammalian target of rapamycin (mTOR) inhibitor to study its effects on rat fibroblast mTOR complex 1 and 2 (mTORC1 & 2) signaling...


read more

Your Price
£205.00 5MG
£246.00 inc. VAT
REQUEST

Application

PP242 hydrate has been used:as a mammalian target of rapamycin (mTOR) inhibitor to study its effects on rat fibroblast mTOR complex 1 and 2 (mTORC1 & 2) signaling as an mTOR inhibitor to treat mouse embryonic fibroblasts (MEF) and cumulus cells (CCs) to study its effects on reactivation of embryonic nucleoli and ribosome biogenesis as a target of rapamycin (TOR) kinase inhibitor for the treatment of Arabidopsis to study its effects against Fusarium graminearum infection

Biochem/physiol Actions

PP242 is a potent and selective mTOR inhibitor. PP242 is a first selective inhibitor that targets ATP domain of mTOR.

Features and Benefits

This compound is featured on the PKB/Akt page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
coloroff-white
formpowder
InChI keyFMDOLJSFPXFBIL-UHFFFAOYSA-N
InChI1S/C16H16N6O.H2O/c1-8(2)22-16-13(15(17)18-7-19-16)14(21-22)12-6-9-5-10(23)3-4-11(9)20-12;/h3-8,20,23H,1-2H3,(H2,17,18,19);1H2
Quality Level100
SMILES stringO.CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c4c(N)ncnc14
solubilityDMSO: >10 mg/mL
storage temp.2-8°C
This product has met the following criteria to qualify for the following awards: