Paroxetine maleate salt, >=98% (HPLC), solid

Code: p1372-10mg D2-231

Biochem/physiol Actions

Paroxetine is a strong cytochrome P450 2D6 isotype (CYP2D6) inhibitor, which reduces the effectiveness of tamoxifen. This phenylpiperidine derivative ...


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£111.00 10MG
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Biochem/physiol Actions

Paroxetine is a strong cytochrome P450 2D6 isotype (CYP2D6) inhibitor, which reduces the effectiveness of tamoxifen. This phenylpiperidine derivative inhibits clozapine metabolism. Paroxetine is used to treat social phobia, obsessive-compulsive disorder and panic disorder. It is also used to treat the premenstrual dysphoric disorder, post-traumatic stress disorder and chronic headache.

Paroxetine maleate is a selective serotonin reuptake inhibitor; antidepressant.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold with the permission of GlaxoSmithKline

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to off-white
formsolid
Gene Informationhuman ... SLC6A4(6532)
InChI keyAEIUZSKXSWGSRU-QXGDPHCHSA-N
InChI1S/C19H20FNO3.C4H4O4/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;5-3(6)1-2-4(7)8/h1-6,9,14,17,21H,7-8,10-12H2;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,17-;/m0./s1
originatorGlaxoSmithKline
Quality Level100
SMILES stringOC(=O)C=C/C(O)=O.Fc1ccc(cc1)[C@@H]2CCNC[C@H]2COc3ccc4OCOc4c3
solubilityDMSO: ~12 mg/mL, H2O: insoluble
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
P1372-50MG
Paroxetine maleate salt, >=98% (HPLC), solid

Unit:50MG
List Price: £550.00
Source:List Price
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Cas Number64006-44-6
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