(+/-)-alpha-Lipoic acid, synthetic, >=99% (titration), powder

Code: t5625-50g D2-231

Application

α-LA can reinstate endothelial activities and alleviate oxidative stress in high-fat fed diabetic rats4. It has also been used to analyze ROS prod...


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Your Price
£637.00 50G
£764.40 inc. VAT

Application

α-LA can reinstate endothelial activities and alleviate oxidative stress in high-fat fed diabetic rats4. It has also been used to analyze ROS production in astrocytes5.

Biochem/physiol Actions

Antioxidant and coenzyme needed for the activity of enzyme complexes such as those of pyruvate dehydrogenase and glycine decarboxylase. Exogenous thioctic acid is reduced intracellularly by two or more enzymes. The reduced form then influences a number of cell processes by direct radical scavenging, recycling of other antioxidants, increasing glutathione synthesis, and modulating transcription factor activity particularly that of NF-κB. Decreases the phagocytosis of myelin by macrophages.

Packaging

500 mg in poly bottle

1, 5, 25, 50 g in poly bottle

Preparation Note

(±)-α-Lipoic acid (α-LA) is soluble in ethanol at 50 mg/ml

assay≥99% (titration)
biological sourcesynthetic
descriptionOxidized form
formpowder
Gene Informationhuman ... ACHE(43), BCHE(590)rat ... Adra1a(29412), Adra1b(24173), Adra1d(29413)
InChI keyAGBQKNBQESQNJD-UHFFFAOYSA-N
InChI1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)
Quality Level200
SMILES stringOC(=O)CCCCC1CCSS1
solubilityethanol: soluble 50 mg/mL
Code
Description
Unit Size
List Price
Qty
T5625-1G
Unit:1G
List Price: £31.70
Source:List Price
ADD
T5625-25G
Unit:25G
List Price: £345.00
Source:List Price
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T5625-500MG
Unit:500MG
List Price: £21.90
Source:List Price
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T5625-5G
Unit:5G
List Price: £106.00
Source:List Price
ADD
Cas Number1077-28-7
This product has met the following criteria: