p-Fluorohexahydro-sila-difenidol hydrochloride, powder, >=98% (HPLC)

Code: h127-10mg D2-231

Application

p-Fluorohexahydro-sila-difenidol hydrochloride (pFHHSid) has been used:as the M3/muscarinic acetylcholinereceptor antagonist to study its involvement in carbachol...


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£313.00 10MG
£375.60 inc. VAT
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Application

p-Fluorohexahydro-sila-difenidol hydrochloride (pFHHSid) has been used:as the M3/muscarinic acetylcholinereceptor antagonist to study its involvement in carbachol induced Egr-1 biosynthesis using human neuroblastoma cellsas M3 receptor antagonist to test its involvement on N,N-diethyl-m-toluamide (DEET)-induced angiogenesis in human umbilical venous endothelial cells (HUVEC)in a study to examine the role of aclidinium on human fibroblast to myofibroblast

Biochem/physiol Actions

High affinity M3 muscarinic acetylcholine receptor antagonist.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
Gene Informationhuman ... CHRM3(1131)
InChI keyJMTYYLMGSBSPPK-UHFFFAOYSA-N
InChI1S/C20H32FNOSi.ClH/c21-18-10-12-20(13-11-18)24(23,19-8-3-1-4-9-19)17-7-16-22-14-5-2-6-15-22;/h10-13,19,23H,1-9,14-17H2;1H
Quality Level100
SMILES stringCl[H].O[Si](CCCN1CCCCC1)(C2CCCCC2)c3ccc(F)cc3
solubilityH2O: slightly soluble 1.5 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: >14 mg/mL, ethanol: soluble
Cas Number116679-83-5
This product has met the following criteria: