Spermine tetrahydrochloride, BioUltra, for molecular biology, >=99.5% (AT)

Code: 85605-5g D2-231

Application

Used to precipitate DNA from low salt aqueous buffers.

Biochem/physiol Actions

Mixed NMDA agonist/antagonist at the polyamine site. N...


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Application

Used to precipitate DNA from low salt aqueous buffers.

Biochem/physiol Actions

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Mixed NMDA agonist/antagonist at the polyamine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Other Notes

Spermine precipitation of DNA

λ1 M in H2O
anion tracessulfate (SO42-): ≤50 mg/kg
assay≥99.5% (AT)
cation tracesBi: ≤5 mg/kg, Na: ≤50 mg/kg, Mo: ≤5 mg/kg, Al: ≤5 mg/kg, K: ≤50 mg/kg, As: ≤0.1 mg/kg, Li: ≤5 mg/kg, Cr: ≤5 mg/kg, Mn: ≤5 mg/kg, Sr: ≤5 mg/kg, Mg: ≤5 mg/kg, Ca: ≤10 mg/kg, Pb: ≤5 mg/kg, Cu: ≤5 mg/kg, Ba: ≤5 mg/kg, Fe: ≤5 mg/kg, Zn: ≤5 mg/kg, Ni: ≤5 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg
formpowder
gradefor molecular biology
impuritiesphosphatases, none detected, RNases, none detected, proteases, none detected, insoluble matter, passes filter test, DNases, none detected
InChI keyXLDKUDAXZWHPFH-UHFFFAOYSA-N
InChI1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
mp310-311 °C (dec.) (lit.)
pH4.5-7.0 (25 °C, 1 M in H2O)
product lineBioUltra
Quality Level300
SMILES stringCl.Cl.Cl.Cl.NCCCNCCCCNCCCN
solubilityH2O: 1 m at 20 °C, clear, colorless to almost colorless
UV absorptionλ: 280 nm Amax: 0.15, λ: 260 nm Amax: 0.2
Code
Description
Unit Size
List Price
Qty
85605-1G
Spermine tetrahydrochloride, BioUltra, for molecular biology, >=99.5% (AT)

Unit:1G
List Price: £62.30
Source:List Price
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85605-25G
Spermine tetrahydrochloride, BioUltra, for molecular biology, >=99.5% (AT)

Unit:25G
List Price: £1,120.00
Source:List Price
ADD
Cas Number306-67-2
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