L-Tryptophan, BioUltra, >=99.5% (NT)

Code: 93659-10g D2-231

Application

L-Tryptophan has been used as a nutritional supplement to study its effect on the circadian clock of primary cell lines. It has also been used as a test amino aci...


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Application

L-Tryptophan has been used as a nutritional supplement to study its effect on the circadian clock of primary cell lines. It has also been used as a test amino acid aerosol to study the variation in the fluorescence intensity of thermally-exposed bacterial bioaerosols.

Biochem/physiol Actions

Tryptophan (Trp) is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Increased Trp availability is necessary for the regulation of mood, cognition and behaviour. It is hypothesised that L-Trp might be useful in inducing sleep in healthy adults against the normal circadian rhythm. Trp uptake by the brain depends on the plasma ratio of Trp to all of the other LNAAs (large neutral amino acids). Higher the Trp:LNAAs ratio, greater is the Trp uptake.

Legal Information

Sephadex is a registered trademark of Cytiva

Sepharose is a registered trademark of Cytiva

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 93659.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Amino acid precursor of serotonin and melatonin

In tryptophan-substituted Sephadex® and Sepharose® for the improved chromatographic separation of cellulases; As spacer in isotachophoresis of serum proteins; Growth requirement of various microorganisms.

absorptioncut-off at 326 nm in 0.5 M HCl at 0.5 M
anion tracessulfate (SO42-): ≤50 mg/kg, chloride (Cl-): ≤50 mg/kg
application(s)cell analysis
assay≥99.5% (NT)
cation tracesBi: ≤5 mg/kg, Na: ≤50 mg/kg, Mo: ≤5 mg/kg, Al: ≤5 mg/kg, K: ≤50 mg/kg, As: ≤0.1 mg/kg, Li: ≤5 mg/kg, Cr: ≤5 mg/kg, Mn: ≤5 mg/kg, Sr: ≤5 mg/kg, Mg: ≤5 mg/kg, Ca: ≤10 mg/kg, Pb: ≤5 mg/kg, Cu: ≤5 mg/kg, Ba: ≤5 mg/kg, Fe: ≤5 mg/kg, Zn: ≤5 mg/kg, Ni: ≤5 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg
colorwhite
formpowder or crystals
ign. residue≤0.1%
impuritiesinsoluble matter, passes filter test
InChI keyQIVBCDIJIAJPQS-VIFPVBQESA-N
InChI1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
loss≤0.1% loss on drying, 20 °C (HV)
mp280-285 °C (dec.) (lit.)
optical activity[α]20/D −31.5±1°, c = 1% in H2O
product lineBioUltra
Quality Level100
SMILES stringN[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
solubility0.5 M HCl: 0.1 g/mL at 20 °C, clear, colorless to faintly yellow
Code
Description
Unit Size
List Price
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93659-250G
L-Tryptophan, BioUltra, >=99.5% (NT)

Unit:250G
List Price: £975.00
Source:List Price
ADD
93659-50G
L-Tryptophan, BioUltra, >=99.5% (NT)

Unit:50G
List Price: £269.00
Source:List Price
ADD
Cas Number73-22-3
This product has met the following criteria: