Application
Vancomycin, from Streptomyces orientalis, is used for the treatment of serious or severe infections caused by susceptible strains of methicillin-resistant (β-lactam-resistant) staphylococci. It is used to block bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis. It is widely studied in cancer patients. Vancomycin′s overuse has been studied, which has resulted in recommended guidelines.
Biochem/physiol Actions
Vancomycin is a glycopeptide antibiotic that blocks bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis. It inhibits incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. It is effective against Gram-positive bacteria. Vancomycin also alters bacterial-cell-membrane permeability and RNA synthesis.
Glycopeptide antibioticMode of action: Used to block bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis by inhibiting incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides.Antimicrobial spectrum: Gram-positive bacteria
General description
Chemical structure: glycopeptide
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
Packaging
100, 250 mg in glass bottle
Bottomless glass bottle. Contents are inside inserted fused cone.
1, 5 g in glass bottle
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