Application
tert-Butyl acetoacetate may be used in the synthesis of:various acetoacetic acid derivativesacetoacetatesacetoacetamides1-(diethylamino)-2-acetoacetoxypropane(S)-tert-butyl 3-hydroxybutyratebenzothiazole β-keto ester derivatives3,4-disubstituted pyrroles
General description
tert-Butyl acetoacetate (t-BAA) is a cheap and easy to store commercial reagent. Reaction demonstrated that the more hindered tert-butyl acetoacetate (t-BAA, la) is ca.15-20-fold more reactive than the more commonly used methyl or ethyl analogs. It is widely employed as an acetoacetylating reagent.
Packaging
1, 4 L in poly bottle
100, 500 mL in poly bottle
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