Application

Dexamethasone is used to study apoptosis, cell signaling pathways, cell differentiation and gene expression.

Biochem/physiol Actions

It is poorly metabolized in the body and has great affinity and bioavailability.

Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

Packaging

1 g in glass bottle

25, 100, 500 mg in glass bottle

Bottomless glass bottle. Contents are inside inserted fused cone.

Physical form

powder 2-8 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw

Reconstitution

To prepare 20 µg/ml stock solution, add 1ml absolute ethanol per mg product; gently swirl to dissolve. Add 49 ml sterile medium per ml of ethanol added, while mixing, to acheive final concentration of 20 µg/ml.