Application

Analytes: GCP2, HCC-1, I-TAC, IL-11, IL-29, Lymphotactin, M-CSF, MIG, MIP-3α, MIP-3β, NAP2 Recommended Sample type: Serum, plasma, and cell culture supernatants Recommended Sample dilution: Neat plasma or serum. A 1:100 dilution is required for NAP-2 and HCC-1 for serum and plasma samples Assay Run Time: Overnight or two-hour primary incubation. For best results, an overnight incubation is recommended Research Category: Inflammation & Immunology Research Subcategory: Obesity, Metabolic Disorders, Inflammation & Autoimmune Mechanisms

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

General description

“Cytokine” is a general term used for a diverse group of soluble proteins and peptides which act as regulators under both normal and pathological conditions to modulate the functional activities of individual cells and tissues. These proteins also mediate direct interactions between cells and regulate processes taking place in the extracellular environment. The cytokine group of proteins includes lymphokines, interferons, colony stimulating factors and chemokines. Cytokine and chemokine research plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, as well as disease states such as inflammatory disease, allergic reactions, irritable bowel disease (IBD), sepsis, and cancer. The MILLIPLEX^® Human Cytokine / Chemokine Panel III enables you to focus on the therapeutic potential of cytokines as well as the modulation of cytokine expression. The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume. Panel Type: Cytokines/Chemokines

Legal Information

xMAP is a registered trademark of Luminex Corp

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Please note: Sample Type must be selected when configuring this kit. HCC-1/CCL14a and NAP-2/CXCL7 cannot be plexed with other analytes for serum/plasma.

Sensitivity: Refer to kit protocol for sensitivities of individual cytokines/chemokines.

Packaging

Everything you need in a single kit.

Specificity

Cross ReactivtyCross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Storage and Stability

Recommended storage for kit components is 2 - 8°C.