Ethylenediaminetetraacetic acid disodium salt dihydrate, meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0%

Code: 27285-500g-r D2-231

Application

Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

Ethylenediaminetetraacetic acid disodi...


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£185.00 500G
£222.00 inc. VAT

Application

Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

Ethylenediaminetetraacetic acid disodium salt dihydrate has been used along with Na2HPO4 and citric acid for preparing Na2EDTA-McIlvaine buffer. Aqueous solution of Ethylenediaminetetraacetic acid disodium salt dihydrate has also been used for photocatalytic hydrogen production

Biochem/physiol Actions

Ethylenediaminetetraacetic acid disodium salt dihydrate is a widely used chelator of divalent cations like Ca+2 and inhibits metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA also acts as a chelator of the zinc ion in the active site of metalloproteases; thus it inhibits metalloproteases that requires zinc for activity. Additionally, EDTA prevents platelet aggregation and is a preferred anticoagulant for platelet counts.

agencytested according to BP, tested according to Ph. Eur., tested according to USP
anion traceschloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤500 mg/kg
application(s)pharmaceutical (small molecule)
assay99.0-101.0%
cation tracesFe: ≤10 mg/kg, As: ≤1 mg/kg, Ca:, in accordance, Pb: ≤10 mg/kg
impurities≤0.001% heavy metals (as Pb), ≤0.001% cyanide (CN), ≤0.1% nitrilotriacetic acid (HPLC) (HPLC), residual solvents, complies
InChI keyOVBJJZOQPCKUOR-UHFFFAOYSA-L
InChI1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
loss8.7-11.4% loss on drying, 200 °C, 3 h
mp248 °C (dec.) (lit.)
pH4-5 (20 °C, 5%)
Quality Level200
qualitymeets analytical specification of Ph. Eur., BP, USP, FCC
reg. compliancetested according to FCC
SMILES stringO.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
solubilitywater: soluble 100 g/L at 20 °C
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Cas Number6381-92-6
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