General description
CHIROBIOTIC® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. Separations normally obtained on a chiral crown ether or ligand exchange-type CSPs are also possible on the CHIROBIOTIC® T and T2, but in much simpler mobile phases, like water-alcohol. In addition, all of the known beta-blockers (amino alcohols), and dihydrocoumarins have been resolved. CHIROBIOTIC® T and T2 differ in their bonding chemistry and the pore size of the support particle, giving them different selectivity and preparative capacity. Bonded phase: Teicoplanin Operating pH range: 3.8 - 6.8 Particle diameter: 5, 10 or 16 µm Pore size: 100 Å (CHIROBIOTIC® T) or 200 Å (CHIROBIOTIC® T2) CHIROBIOTIC FAQsCHIROBIOTIC Reference BibliographyChiral Product Literature
Legal Information
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
Astec is a registered trademark of Sigma-Aldrich Co. LLC
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