BIOshell A160 Peptide CN, 5 mum HPLC Column, 4.7 mum particle size, L x I.D. 15 cm x 3 mm

Code: 67069-u D2-231

General description

BIOshell™ 160 Å Peptide CN columns provide an alternative selectivity to the traditional C18 bonded phases. The introduction of the cyano...


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General description

BIOshell™ 160 Å Peptide CN columns provide an alternative selectivity to the traditional C18 bonded phases. The introduction of the cyano group enables peptides and small proteins to be separated due to a combination of hydrophobicity and dipole-dipole interactions making this column an excellent choice for biomolecules that are not resolved on traditional C18 columns. These columns contain advanced Fused-Core particles with pores strategically sized to 160 Å to enable optimized peptide diffusion. This attribute makes these columns an excellent choice for peptide mapping. Additionally, the sterically-protected cyanopropyl ligands provide extra stability allowing the columns to be used at an extended pH range (2-9) and high temperatures (up to 90 °C).

Legal Information

BIOshell is a trademark of Sigma-Aldrich Co. LLC

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agencysuitable for USP L10
analyte chemical class(es)peptides
descriptionSolid Core (3.5 µm), Shell thickness (0.6 µm)
extent of labeling1.5% carbon loading
featureendcapped
L × I.D.15 cm × 3 mm
manufacturer/tradenameBIOshell™
materialstainless steel hardware (column)
matrix active groupcyano phase
matrixsuperficially porous particle, spherical silica particle platform
operating pH range1-8
packaging1 ea of
parameter90 °C max. temp., 600 bar max. pressure
particle size5.0 µm
pore size160 Å
product lineBIOshell™
Quality Level100
separation techniquenormal phase, hydrophilic interaction (HILIC), reversed phase
surface area60 m2/g
surface coverage2.2 µmol/m2
technique(s)UHPLC-MS: suitable, HPLC: suitable, LC/MS: suitable, UHPLC: suitable
This product has met the following criteria: