Cytidine-5-monophospho-N-acetylneuraminic acid sodium salt, >=85% (HPLC)

Code: c8271-1mg D2-231

Application

Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt has been used: as a standard in high-performance anion-exchange chromatography with pulsed am...


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Application

Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt has been used: as a standard in high-performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD) for nucleotide sugar analysis in Joubert syndrome type 10 (JBTS10) patient cells and control skin fibroblasts, As a substrate for the enzymatic sialylation of G2 glycoforms, resialylation assay, in in-vitro sialyltransferase assay

Biochem/physiol Actions

Cytosine 5′-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac) is used as a substrate for Golgi sialyltransferases to form sialic acid and its conjugates.

Cytidine-5′-monophospho-N-acetylneuraminic acid (CMP-Sialic acid) is a substrate for sialyltransferases. It is used for the enzymatic sialylation of glycans.

General description

Cytosine 5′-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac) is a sugar-nucleotide produced by CMP-Neu5Ac synthetase from CTP and Neu5Ac.

Packaging

1, 5 mg in glass bottle

25 mg in poly bottle

Preparation Note

Enzymatically prepared by the method of Schauer, R., et al., Hoppe Seyler′s Z. Physiol. Chem., 353, 883 (1972).CMP-NAN is very acid-labile.

assay≥85% (HPLC)
formpowder
InChI keyVFRHSOGUONIUOR-CTFMUGKASA-M
InChI1S/C20H31N4O16P.Na/c1-7(26)22-12-8(27)4-20(18(32)33,39-16(12)13(29)9(28)5-25)40-41(35,36)37-6-10-14(30)15(31)17(38-10)24-3-2-11(21)23-19(24)34;/h2-3,8-10,12-17,25,27-31H,4-6H2,1H3,(H,22,26)(H,32,33)(H,35,36)(H2,21,23,34);/q;+1/p-1/t8-,9+,10+,12+,13+,14+,15+,16?,17+,20+;/m0./s1
Quality Level200
SMILES string[Na+].CC(=O)N[C@@H]1[C@@H](O)C[C@@](O[C@@H]1[C@H](O)[C@H](O)CO)(OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(N)=NC3=O)C(O)=O
storage temp.−20°C
Code
Description
Unit Size
List Price
Qty
C8271-25MG
Cytidine-5-monophospho-N-acetylneuraminic acid sodium salt, >=85% (HPLC)

Unit:25MG
List Price: £1,190.00
Source:List Price
ADD
C8271-5MG
Cytidine-5-monophospho-N-acetylneuraminic acid sodium salt, >=85% (HPLC)

Unit:5MG
List Price: £332.00
Source:List Price
ADD
Cas Number3063-71-6
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