Isovaleryl coenzyme A lithium salt hydrate, >=90%

Code: i9381-10mg D2-231

Application

Isovaleryl coenzyme A (IV-CoA ) lithium salt hydrate may be used:as substrate for β-Hydroxy-β-methylbutyric acid synthesis in cell-free extracts from G. reess...


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£336.00 10MG
£403.20 inc. VAT
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Application

Isovaleryl coenzyme A (IV-CoA ) lithium salt hydrate may be used:as substrate for β-Hydroxy-β-methylbutyric acid synthesis in cell-free extracts from G. reessiiin high-performance liquid chromatography (HPLC) for the characterization of IV-CoA from lymphocytesas a substrate in isovaleryl-CoA dehydrogenase assay

General description

Isovaleryl coenzyme A is an intermediate in leucine catabolism. Iv-CoA is synthesized from β-methylbutyric acid by the action of enzyme acyl CoA synthetase. The conversion of isovaleryl-CoA to methylcrotonyl-CoA is catalyzed by the enzyme isovaleryl-CoA dehydrogenase in leucine catabolism pathway. The enzyme isovaleryl-CoA oxidase also calalyzes this conversion in fatty acid β-oxidation pathway.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. I9381.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Packaging

10 mg in glass bottle

assay≥90%
InChI keyRABPIYFVNICBEC-YVBWDKSKSA-K
InChI1S/C26H44N7O17P3S.3Li.H2O/c1-14(2)9-17(35)54-8-7-28-16(34)5-6-29-24(38)21(37)26(3,4)11-47-53(44,45)50-52(42,43)46-10-15-20(49-51(39,40)41)19(36)25(48-15)33-13-32-18-22(27)30-12-31-23(18)33;;;;/h12-15,19-21,25,36-37H,5-11H2,1-4H3,(H,28,34)(H,29,38)(H,42,43)(H,44,45)(H2,27,30,31)(H2,39,40,41);;;;1H2/q;3*+1;/p-3/t15-,19-,20-,21+,25-;;;;/m1..../s1
Quality Level200
SMILES string[Li+].[Li+].[Li+].[H]O[H].CC(C)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)([O-])=O)n2cnc3c(N)ncnc23
storage temp.−20°C
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