Application
Proton scavenger used in peptide coupling, enolboration, Pd(0)-catalyzed alkoxycarbonylation of allyl phosphates and acetates, and as a catalyst in vinyl sulfone synthesis.
N,N-Diisopropylethylamine may be used in the synthesis of mannosylated ovalbumin peptides.
General description
N,N-Diisopropylethylamine, also known as Hünig′s base, is a sterically hindered amine. It is a non-nucleophilic base commonly employed for substitution reactions. It acts as an activator for chiral iridium N, P ligand complexes, which can be utilized in the hydrogenation of α, β-unsaturated nitriles. The influence of varying concentration of N,N-diisopropylethylamine on the synthesis of olvanil in the presence of lipase catalyst has been investigated.
Legal Information
ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC
Packaging
10, 50 L in composite drum
100, 4×100, 500 mL in glass bottle
1, 2.5 L in glass bottle
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