BrettPhos Pd G1 Methyl-t-Butyl Ether Adduct, may contain up to 1 mole equivalent of MTBE, 97%

Application

Application Guide for Palladium Catalyzed Cross-Coupling ReactionsCatalyst for: C,N-cross coupling of unprotected 3-halo-2-aminopyridines with primary and secondary amines Amination reaction N-arylation of aminophenols

General description

BrettPhos Pd G1 is a Buchwald first generation (G1) palladacycle precatalyst that can be used in cross-coupling reactions for the formation of C-C, C–N, C–O, C–F, C–CF3, and C–S bonds. The formation of the active Pd(0) species in the G1 precatalyst is easy to generate, requiring merely a deprotonation with a base. The resulting catalyst is very active, even at temperatures down to −40 °C, and can be used in a variety of cross-coupling protocols.

Packaging

100 mg in glass bottle

1, 5 g in glass bottle