Dexamethasone, pharmaceutical secondary standard; traceable to USP, PhEur, BP

Code: phr1526-1g D2-231

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Application

T...


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£110.65 1G
£132.78 inc. VAT

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Dexamethasone may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using voltammentric techniques and reversed-phase high-performance liquid chromatography technique.

Biochem/physiol Actions

Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2894 in the slot below. This is an example certificate only and may not be the lot that you receive.

General description

Dexamethasone is a corticosteroid medication, with anti-inflammatory activity. It is widely used for inflammatory ocular conditions and for the treatment of skin-allergic reactions.Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

agencytraceable to BP 578, traceable to Ph. Eur. D0700000, EP, USP, traceable to USP 1176007, BP
application(s)pharmaceutical (small molecule)
biological sourcesynthetic
CofAcurrent certificate can be downloaded
colorwhite
formatneat
Gene Informationhuman ... NR3C1(2908)
gradepharmaceutical secondary standard, certified reference material
InChI keyUREBDLICKHMUKA-CXSFZGCWSA-N
InChI1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
mp262-264 °C (lit.)
packagingpkg of 1 g
Quality Level300
shipped inambient
SMILES stringC[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
solubilitydioxane: soluble, methanol: sparingly soluble, chloroform: slightly soluble, acetone: sparingly soluble, ether: very slightly soluble, DMSO: soluble, ethanol: sparingly soluble, water: practically insoluble
storage conditionprotect from light
storage temp.2-30°C
technique(s)gas chromatography (GC): suitable, HPLC: suitable
vapor pressure﹤0.0000001 kPa ( 25 °C)
Cas Number50-02-2
This product has met the following criteria: