alpha-Crystallin from bovine eye lens, lyophilized powder

Code: c4163-5mg D2-231

Application

α-Crystallin is a lens protein that contains two homologous subunits: αA- and αB-crystallins. α-Crystallin displays chaperone-like activity an...


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Your Price
£133.14 5MG
£159.77 inc. VAT

Application

α-Crystallin is a lens protein that contains two homologous subunits: αA- and αB-crystallins. α-Crystallin displays chaperone-like activity and plays an important role in maintaining lens transparency. It has been noted that in diabetic conditions of rats there is a decline in the chaperone activity of α-Crystallin. Research has shown that a dietary antioxidant, curcumin, can prevent this loss of chaperone activity.

Biochem/physiol Actions

α-Crystallin is a small heat-shock protein that has chaperone-like activity, preventing protein aggregation in vitro. Point mutations in α-crystallin genes are believed to be responsible for hereditary cataract development.

Packaging

5 mg in glass bottle

25 mg in poly bottle

assay≥70% (biuret)
biological sourcebovine eye (lens)
formlyophilized powder
Gene Informationbovine ... CRYAA(281718), CRYAB(281719)
Quality Level200
storage temp.−20°C
technique(s)cell culture | mammalian: suitable
UniProt accession no.P02470, P02510
Code
Description
Unit Size
List Price
Qty
C4163-25MG
Unit:25MG
List Price: £503.17
Source:List Price
ADD
Cas Number11046-99-4
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