Application

Mucin from bovine submaxillary glands has been used: in the quantification of mucinas a component of artificial tear solutionas a substrate for recombinant sialidase Gardnerella vaginalisto investigate a galactose-specific lectin from the red marine alga Ptilota filicinato study the characterization of a unique mucin-like glycoprotein secreted by a human endometrial adenocarcinoma cell line (Ishikawa)

Biochem/physiol Actions

Albuminoid substance in mucus which gives it its ropy consistency

Bovine submaxillary mucin (BSM) is thermally stable up to 85°C. The terminal domain regions are key for the adsorption functionality of mucin.

General description

Mucin from bovine submaxillary glands is encoded by two bovine submaxillary BSM genes. It is present in the saliva and interacts with air and food. Mucin comprises three major domains namely N- and C terminal and the glycosylated proline, threonine and serine (PTS domain) central domain. The sialic acid contributes to 30% of the molecular weight of mucin. The central domain has many tandem repeats.

Linkage

Similar to M 4503, but produced by Sigma.

Packaging

100, 500 mg in poly bottle

1 g in poly bottle

Substrates

Neuraminidase substrate.