Human NRG-1 protein (neuregulin 1) is frequently used in the maintenance of human pluripotent stem cells. In addition to its widespread use in stem cell culture media, NRG-1 (also known as Heregulin-β1 , HRG-1) has essential roles in vivo including in nervous system, cardiac, and mammary gland development; cancer biology and neurological disorders.

7.5 kDa highly pure, bioactive domain of human NRG-1, comprised of the β isoform of the EGF-like domain of NRG-1 (HRG1-B1). This NRG-1 protein monomer is animal origin-free (AOF) and carrier-protein free (CF).

• High purity human NRG-1 protein (Uniprot:Q02297)
• >98%, by SDS-PAGE quantitative densitometry
• 7.5 kDa
• Expressed in E. coli
• Animal origin-free (AOF) and carrier protein-free
• Manufactured in our Cambridge, UK laboratories
• Lyophilised from acetonitrile, TFA
• Resuspend in water at >100µg/mL, prepare single use aliquots, add carrier protein if desired and store frozen at -20°C or -80°C