Amino Acid Sequence
Boc-Bal-Trp-Met-Asp-Phe-NH2
Application
Pentagastrin has been used to bidirectionally modulate lateral nucleus of the amygdala (LA) activity.
Biochem/physiol Actions
CCKB agonist that stimulates gastric acid secretion; anxiogenic.Pentagastrin is an agonist of the cholecystokinin-2 (CCK2) receptor. It helps to increase the excitability of neurons in the basolateral amygdala through the activation of a non-specific cation channel.
General description
CCK2R (cholecystokinin 2 receptor) is also referred as CCKBR. It is a G-protein coupled receptor, that is expressed in the central nervous system and throughout the gastrointestinal tract. CCK2R is located on human 11p15.
Packaging
25, 100 mg in serum bottle
This product has met the following criteria: