QuikPrep® SpinColumns™ for normal phase chromatography are packed with a stationary polar phase. Available matrixes include: Cyano (CN), Amino (NH₂) and PHEA (Polyhydroxyethyl Aspartamide) and Silica. Normal phase chromatography uses a spin column packed with a stationary polar phase, and a non-polar mobile phase is passed through the column. Molecules with similar polarities attract one another causing the least polar compounds to elute first as the more polar compounds are held by the polar matrix. These polar compounds can then be released through the addition of an elution buffer.